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administering-hpc

Mentors and Regional Facilitators
Name Region Skills Interests
Aaron Jezghani Campus Champions
Al Tucker Campus Champions
Michael Blackmon Campus Champions, ACCESS CSSN
Brandon Biggs OnDemand
Brian Haymore Campus Champions, RMACC, CCMNet
Christina Divoll Campus Champions, ACCESS CSSN
Charles Forsyth Campus Champions
Chad Julius Campus Champions, Great Plains
Cody Stevens Campus Champions, CCMNet
Michael Conner Campus Champions
Stephen Cousins Campus Champions
Craig Earley RMACC
Chris Reidy Campus Champions, CCMNet
Edwin Posada Campus Champions
Jeff Falgout Campus Champions, RMACC
Jacob Fosso Tande ACCESS CSSN, Campus Champions, CCMNet
Jack Garmer Campus Champions
Jordan Hayes Campus Champions
Jonathan Komperda Campus Champions
Jeffrey Weekley Campus Champions
Jason Wells ACCESS CSSN, Campus Champions
Jason Yalim Campus Champions
James Hutcheson Campus Champions, ACCESS CSSN
Michael Schnaitter ACCESS CSSN
Nick Dusek Campus Champions
Nannan Shan CCMNet, ACCESS CSSN
Paul Gluhosky Campus Champions
Lev Gorenstein CCMNet
Mike Renfro Campus Champions, CCMNet
Ric Anderson Campus Champions
Ruben Lara Campus Champions
Sean Anderson ACCESS CSSN, Campus Champions, CCMNet, OnDemand
Sumit Saluja Campus Champions
Sathish Srinivasan ACCESS CSSN
Torey Battelle Campus Champions, CCMNet
Timothy Middelkoop ACCESS CSSN, Campus Champions, CCMNet, Great Plains
Trey Breckenridge Campus Champions
William Lai ACCESS CSSN
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Affinity Groups

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Account and Access Management CI Facilitators A group for CI and RCD professionals responsible for developing and maintaining the Account and Access Management solutions used at their institutions. Participants are invited to share and discuss… Login to join
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Topics from Ask.CI

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Engagements

Re-engineering Lilly’s KisunlaTM into a novel antibody targeting IL13RA2 against GBM using AI-driven macromolecular modeling
Atrium Health Levine Cancer
  • Summary and objectives of the proposed experiments: 
  1. An initial research-based Ab (scFv47, discovered by our collaborator Dr. Balyasnikova) model, modeling Ab-Ag (IL13RA2 against GBM) protein complex, and identifying the binding sites (epitopes) using ROSETTA and AlphaFold2 multimer tools.
  2. Graft the CDRs of scFv (single-chain variable fragment) of antibody or Bispecific T cell engagers (BTEs) onto the template Ab, the framework of Lilly's Kisunla™ Ab drug.
  3. Modify, improve, and optimize the overall or full antibody protein structures using AI-driven macromolecule modeling (AlphaFold3).
  4. Explore single nucleotide polymorphism (SNP), pathogenic genetic variants and N-glycosylation of IL13RA2 (target) protein domain interacting with the Ab candidates among the patient population using ROSETTA software packages.
Status: In Progress

People with Expertise

Sathish Srinivasan

Programs

ACCESS CSSN

Roles

mentor, researcher/educator, research computing facilitator, research software engineer, cssn

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Expertise

Stephen Cousins

University of Maine System

Programs

Campus Champions

Roles

research computing facilitator

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Expertise

Michael Conner

Grinnell College

Programs

Campus Champions

Roles

research computing facilitator

Expertise

People with Interest

Rachael Auch

South Dakota State University

Programs

Great Plains, Campus Champions, CCMNet

Roles

mentor, research computing facilitator, regional admin, CCMNet

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Interests

Samantha Granja

Programs

ACCESS CSSN

Roles

student-facilitator

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Interests

Benjamin Meyers

Rochester Institute of Technology

Programs

Campus Champions

Roles

research computing facilitator

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Interests